CLiC 2019 Q2: Regarding MURANO 48-month data presented at iwCLL conference 2019, reviewed in Dr. Owen's podcast: (1) Should MRD testing (positive MRD) be used to tailor treatment with VR given 27% of patients who discontinued treatment have now progressed? (2) Should high risk cytogenetics be used to tailor treatment with VR given 27% of patients who discontinued treatment have now progressed? (3) Should everyone stop treatment at 24 months?


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